Selank

Buy Selank Peptide | Pure Anxiolytic Nootropic Heptapeptide | PrimaLab Peptide

Selank (also designated TP-7) is a synthetic heptapeptide analogue of tuftsin — a naturally occurring immunomodulatory tetrapeptide — developed at the Institute of Molecular Genetics of the Russian Academy of Sciences. Researchers who buy Selank peptide use it to investigate anxiolytic mechanisms, GABA-A receptor interactions, enkephalin enzyme inhibition, immune system modulation, and nootropic pathways in cell culture and animal research models. With a published research history spanning several decades — primarily from Russian and Eastern European research institutions — Selank has a solid and independently verifiable scientific foundation. PrimaLab Peptide supplies research-grade Selank at ≥99% purity, independently verified by Janoshik Analytical via HPLC and mass spectrometry, with a full batch-specific Certificate of Analysis included with every order.

What Is Selank?

Selank is a synthetic heptapeptide with the amino acid sequence Thr-Lys-Pro-Arg-Pro-Gly-Pro (molecular formula C₃₃H₅₇N₉O₈, MW 751.87 g/mol). It was developed as a structurally extended and metabolically stabilised analogue of tuftsin — the endogenous tetrapeptide Thr-Lys-Pro-Arg, a fragment of IgG immunoglobulin — by the addition of a Pro-Gly-Pro C-terminal extension that confers improved metabolic stability and extended biological half-life compared to the parent tuftsin molecule.

Selank’s development emerged from research into tuftsin’s immunomodulatory and CNS-active properties, with the goal of producing a compound that retained and enhanced tuftsin’s research-relevant biological activities while resisting rapid enzymatic degradation. The result is a heptapeptide with a distinct and well-characterised research profile spanning anxiolytic, nootropic, and immunomodulatory mechanisms. A broad overview of Selank’s research background is available through published PubMed research on Selank.

Selank vs. Semax — Clearing Up the Confusion

Selank and Semax are frequently conflated by researchers new to nootropic peptide research. They are distinct compounds with different origins, mechanisms, and research applications:

• Selank (this product): Derived from tuftsin (IgG fragment). Sequence Thr-Lys-Pro-Arg-Pro-Gly-Pro. Primary research focus: anxiolytic mechanisms, GABA-A receptor interactions, enkephalin enzyme inhibition, and immune modulation. Research profile emphasises anti-anxiety and immunomodulatory pathways
• Semax: Derived from ACTH(4-7). Sequence Met-Glu-His-Phe-Pro-Gly-Pro. Primary research focus: BDNF and NGF modulation, neuroprotection, cognitive enhancement, and dopaminergic/serotonergic pathway interactions. Research profile emphasises neuroprotective and nootropic mechanisms

These compounds are not interchangeable in research protocols. Confirm your specific research target — anxiolytic/immune pathways (Selank) vs. neuroprotective/BDNF pathways (Semax) — before ordering. Both are available from PrimaLab Peptide’s Nootropic & Neuro Peptides category.

Selank Research Applications

Selank has a solid published research foundation, particularly in Russian and Eastern European scientific literature, with a growing body of work available through international databases. Researchers studying Selank have examined it across the following areas:

• Anxiolytic mechanism research: Selank has been studied extensively for anxiolytic effects in animal research models, with research examining its ability to reduce anxiety-related behaviour through mechanisms distinct from classical benzodiazepine anxiolytics — without the sedative or dependence-associated properties of GABA-A positive allosteric modulators in research models
• GABA-A receptor interaction research: Studies have investigated Selank’s interactions with the GABAergic system, examining how it modulates GABA-A receptor activity and downstream inhibitory neurotransmission without direct receptor binding typical of benzodiazepines
• Enkephalin enzyme inhibition research: Selank has been studied as an inhibitor of enkephalin-degrading enzymes, potentially extending the activity of endogenous enkephalin opioid peptides in research models — a mechanism that contributes to its anxiolytic research profile
• Immune modulation research: As a tuftsin analogue, Selank retains immunomodulatory research properties, with studies examining its effects on interleukin production (particularly IL-6), T-cell activity, and innate immune signalling
• Serotonin and dopamine system research: Studies have examined Selank’s effects on serotonin and dopamine turnover in brain research models, contributing to understanding of its nootropic and mood-related research mechanisms
• Cognitive and memory research: Research has examined Selank’s effects on learning and memory performance in animal research models, a research area that complements its anxiolytic profile
• Intranasal delivery model research: Like Semax, Selank has been studied in intranasal delivery research models due to its short systemic half-life — intranasal delivery bypasses peripheral enzymatic degradation and is relevant to CNS neuropeptide delivery research

Purity & Third-Party Testing

Every batch of Selank supplied by PrimaLab Peptide is independently tested by Janoshik Analytical:

• HPLC — quantitative purity confirmed at ≥99% with clean chromatography showing no significant impurity peaks
• Mass Spectrometry — molecular identity confirmation (C₃₃H₅₇N₉O₈, MW 751.87 g/mol)

The batch-specific COA is included with every order and carries a unique batch number that researchers can cross-reference directly on the Janoshik database to independently verify the result. When reviewing a Selank COA, confirm: HPLC purity ≥99% with clean chromatography, mass spec confirmation of correct MW (751.87 g/mol), and no visible contamination in the lyophilized powder. These are the three verification checkpoints that confirm research-grade quality.

Storage & Reconstitution

Selank is supplied as a lyophilized powder, stable for up to 24 months under correct sealed storage conditions.

• Sealed (lyophilized): Store at −20°C, away from moisture and light. Stable up to 24 months sealed
• After reconstitution: Store at 4°C and use within 28–30 days. Do not re-freeze reconstituted solution
• Reconstitution solvent: Reconstitute with sterile Bacteriostatic Water (BAC Water). Roll the vial gently to mix — never shake or vortex, which damages peptide structure
• Freeze-thaw cycles: Avoid. Each cycle degrades Selank faster than sustained cold storage. Reconstitute only the volume needed for your current research window
• Vial labelling: Label all reconstituted vials with reconstitution date, concentration, and compound identity — basic lab practice that is easy to overlook but essential for research documentation

Product Specifications

Peptide Name	Selank
Also Known As	TP-7
Sequence	Thr-Lys-Pro-Arg-Pro-Gly-Pro
Molecular Formula	C₃₃H₅₇N₉O₈
Molecular Weight	751.87 g/mol
Purity	≥99% (Janoshik HPLC + Mass Spectrometry verified)
Form	Lyophilized powder
Storage (sealed)	−20°C, away from moisture and light
Storage (reconstituted)	4°C, use within 28–30 days
Stability (lyophilized)	24 months sealed
Reconstitution	Bacteriostatic Water (BAC Water)
Testing Lab	Janoshik Analytical (independent third-party)
COA	Batch-specific — included with every order
Intended Use	In-vitro laboratory research only — not for human or veterinary use

Frequently Asked Questions — Selank Peptide

What is Selank used for in research?

Researchers who buy Selank peptide use it to investigate anxiolytic mechanisms distinct from classical benzodiazepines, GABA-A receptor interaction pathways, enkephalin enzyme inhibition, immune system modulation (interleukin regulation, T-cell activity), serotonin and dopamine turnover effects, cognitive and memory performance in animal research models, and intranasal neuropeptide delivery systems. Its well-established research profile makes it one of the most characterised synthetic tuftsin analogues in nootropic and anxiolytic peptide research. Published literature is available on PubMed.

Is Selank the same as Semax?

No — they are distinct research compounds with different origins, sequences, and mechanisms. Selank derives from tuftsin (IgG fragment) and is primarily studied for anxiolytic, GABA-A, and immunomodulatory mechanisms. Semax derives from ACTH(4-7) and is primarily studied for BDNF/NGF modulation and neuroprotective mechanisms. They are not interchangeable in research protocols — confirm your specific research pathway before ordering.

Is Selank from PrimaLab Peptide independently tested?

Yes. Every batch is independently verified by Janoshik Analytical at ≥99% purity via HPLC and mass spectrometry identity confirmation (C₃₃H₅₇N₉O₈, MW 751.87 g/mol). The batch-specific COA is included with every order and cross-referenceable on the Janoshik database. Always match the batch number on your vial to the COA document before use.

What reconstitution solvent should I use for Selank?

Reconstitute Selank with sterile Bacteriostatic Water (BAC Water). Add solvent slowly down the inside wall of the vial and roll gently — never shake or vortex. Store the reconstituted solution at 4°C and use within 28–30 days. Label the vial with reconstitution date and concentration for research documentation.

How does Selank’s mechanism differ from benzodiazepines in anxiolytic research?

Classical benzodiazepines produce anxiolytic effects through direct positive allosteric modulation of GABA-A receptors, enhancing chloride channel conductance. Research on Selank has examined indirect GABAergic pathway modulation and enkephalin enzyme inhibition — mechanisms that are mechanistically distinct from direct GABA-A positive allosteric modulation. This mechanistic distinction is part of what makes Selank an interesting research tool for studying alternative anxiolytic pathways in animal models. See published research on PubMed.

What peptides are commonly researched alongside Selank?

Researchers buying Selank peptide for nootropic and anxiolytic research frequently explore Semax (ACTH analogue for neuroprotective and BDNF research), Oxytocin Acetate (anxiety and amygdala pathway research), and Kisspeptin-10 (neuroendocrine axis research). Browse the full Nootropic & Neuro Peptides category.

Related Research Peptides

Researchers buying Selank peptide frequently explore:

• Semax — ACTH(4-7) analogue for BDNF modulation and neuroprotective pathway research
• Oxytocin Acetate — nonapeptide for anxiety, amygdala, and social behaviour research
• Kisspeptin-10 — KISS1 gene decapeptide for HPG axis neuroendocrine research
• KPV Peptide — alpha-MSH C-terminal tripeptide for anti-inflammatory pathway research
• Thymosin Alpha-1 — immunomodulatory peptide for T-cell and immune function research

Browse our complete Nootropic & Neuro Peptides category. Bulk researchers can apply for discounted rates through our Wholesale Portal. Reconstitute with BAC Water, available in our Accessories & Reconstitution Supplies section.

⚠️ For in-vitro laboratory research use only. Not intended for human or veterinary consumption. Not a drug, supplement, or medical treatment. Researchers are solely responsible for compliance with all applicable local, national, and international regulations. All products are intended exclusively for laboratory research and are not approved by any regulatory authority for human or veterinary use.